Updated October 29, 2026.

Not part of the Oct 28 HHS policy. Compounded NAD+ is not FDA-approved.

What is NAD+?

NAD+ (nicotinamide adenine dinucleotide) is a coenzyme, a helper molecule found in every cell in your body.

Your cells use it to turn food into energy, to support the mitochondria and to help repair DNA.

NAD+ isn't technically a peptide, but it's often offered alongside peptides as part of a healthy aging plan.

Research suggests NAD+ levels decline with age.

What the research is looking at

NAD+ is being studied for its role in:

  • Cellular energy and mitochondrial function
  • Healthy aging
  • Metabolic health
  • Mental clarity and focus

Much of the research so far has been in the lab and in animals, or has used oral NAD+ precursors such as NR and NMN rather than NAD+ itself.

Human studies of NAD+ given directly are small and early, and long-term effects aren't known.

Who it may be for

Adults focused on energy, recovery, mental clarity and healthy aging often ask about NAD+.

Results vary from person to person, and our provider will talk with you about realistic expectations.

Regulatory status

Compounded NAD+ is not FDA-approved. It is not part of the October 28, 2026 HHS peptide policy.

NAD is on FDA's list of compounding ingredients under evaluation. While that review continues, FDA allows state-licensed pharmacies to compound it for individual prescriptions, under certain conditions.

FDA has warned pharmacies not to use food-grade NAD+ for sterile products, because of contamination risk. That's one reason we work with an FDA-inspected 503(a) pharmacy that provides full testing reports.

Read the full FDA update

Safety and side effects

Side effects reported with NAD+ can include:

  • Redness, soreness or a burning feeling where it's given
  • Flushing or a warm feeling
  • Nausea or stomach upset
  • Headache, lightheadedness or tiredness
  • Chest tightness or muscle cramps, which usually ease quickly

NAD+ may not be right for you if:

  • You're pregnant, breastfeeding or trying to conceive.
  • You're under 18.
  • You have active cancer or a history of cancer.
  • You have heart disease or low blood pressure.

Our provider will review your health history before prescribing.

How it works at Optimize Hormone

Optimize Hormone offers these prescription peptides from an FDA-inspected 503(a) pharmacy in the US, with full testing reports, delivered directly to your home.

Our approach to peptide therapy is personalized and provider-guided, designed to support recovery, performance, longevity and overall wellness.

  • Bloodwork membership not required for peptides.
  • Complete your online intake, or book a free consultation if you'd like to talk it through first.
  • Our provider reviews your health history and goals and determines whether NAD+ is appropriate for you.
  • If prescribed, your medication ships to your door with all necessary supplies, plus personalized dosing and instructions from your licensed provider.

How it's delivered

Your prescription arrives pre-mixed and ready to use, with all the supplies you need.

Our provider will walk you through how and when to use it.

Monthly membership: $125/month

Book your free consultation

Start your intake

Common questions

Is NAD+ a peptide?

No. It's a coenzyme, not a peptide, but it's often part of the same healthy aging conversation.

Is this the same as an NAD+ supplement?

No. Oral supplements usually contain precursors such as NR or NMN, which your body converts to NAD+. A prescription NAD+ product is different, and our provider can explain the options.

When might I notice a difference?

It varies. Some people say they notice changes in energy within a few weeks, and others don't. Our provider will set realistic expectations with you.

Do I need bloodwork?

A bloodwork membership is not required for peptides. Our provider may recommend labs based on your health history.

How to get started

1. Complete the short online intake.

2. Or book a free consultation if you'd like to talk it through first.

3. Our provider reviews your answers and lets you know whether NAD+ is a fit for you.

More peptides

Educational information only, not medical advice. Compounded medications are not FDA-approved, which means FDA does not review their safety, effectiveness or quality before they are dispensed. Our provider determines whether any medication is appropriate for you. Regulatory information is current as of October 29, 2026 and may change. Prescriptions are filled by a state-licensed 503(a) compounding pharmacy in the US.